No proof natural compound prevents swine fever, China ag ministry says

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Published: June 13, 2019

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A macrophage (immune response) cell in early stages of infection with African swine fever virus, magnified about 1,000x. (Keith Weller photo courtesy ARS/USDA)

Beijing | Reuters — China’s ministry of agriculture said on Thursday a company which claimed a natural compound was effective in preventing African swine fever did not have government approval to research the virus and its assertions were not scientifically sound.

Shopping mall operator Guangdong Highsun Group was questioned by the Shenzhen Stock Exchange earlier on Thursday after this week announcing it was backing development of an African swine fever vaccine.

Beijing strictly regulates research on, and handling of, the virus.

Highsun said on Tuesday it would spend 900 million yuan (C$172.9 million), or 26 per cent of its 2018 net assets, on supporting research into a natural compound it said had been shown to prevent the disease which is deadly to pigs and ravaging herds across Asia.

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But the ministry said it had not received a research application and without experimental data, the claim that a polysaccharide injection is effective in preventing the virus lacked scientific proof.

Researchers around the world have been trying for years to develop a vaccine against African swine fever without success.

Highsun said that preliminary research had found the polysaccharide to be 92 per cent effective in preventing the disease in clinical trials — an announcement which triggered a 10 per cent surge in its shares on Wednesday, leading to a trading suspension.

The Shenzhen exchange said it was seeking clarity on several issues, including additional data regarding the vaccine’s effectiveness and whether the researchers had government approval to conduct research on the virus.

An official from Highsun, who asked not to be identified, said the company was preparing a response to the exchange’s questions and declined to comment further.

African swine fever kills almost all the pigs it infects. The breeding herd in China, the world’s top pork producer, has declined by a record 24 per cent owing to the disease, the agriculture ministry said on Thursday.

The bureau of agriculture and rural affairs for Hainan province said on its website on Thursday that it had supported a research team that had isolated a polysaccharide compound from tropical plants which had shown a “certain preventive effect” against African swine fever.

However, it said more research was needed in areas including the possible impact of virus mutation and the safety, stability and feasibility of industrial production of the compound.

It is not clear if the bureau was referring to the same team backed by Highsun and it did not answer calls for a comment on the statement.

Highsun’s shares rose 7.3 per cent to 3.38 yuan (65 Canadian cents) a share after resuming trading on Thursday.

— Reporting for Reuters by Dominique Patton, the Reuters Beijing newsroom and Meg Shen in Hong Kong.

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